I knew this, and understood it rationally, but when I had two miscarriages in a row I was still devastated because the heart tends to ignore the brain. I contracted the Kell antibody because of a blood transfusion I had after my 1st pregnancy which was a c-sec. Every one of their kids will have brown eyes because of the B, but they will all be carrying the blue b as well. This means we can use the Punnett square again and see the genotypes of the offspring of a brown-eyed person (BB or Bb) and a blue-eyed person (bb). The B Positive blood type is extremely valuable where matching supply for the demand has been a constant challenge. Or maybe none of them will be. That being said, a Kell+ woman will not have any problems with pregnancy because of her blood type. The #1 explanation for unknown antibodies is a false positive test or clerical error. My sincere hopes for your future reproductive success. I hope you and your new baby are very healthy! What does it mean to be “sex positive?” This is one of those terms that different people define in different ways; however, at the core of most definitions is the idea that we must recognize that human sexuality—in its diverse and myriad forms of expression—is natural and healthy. Actually I checked to be notified by email of follow up comments do we’re good. Is that correct? Path to improved health. I feel like a blood group freak. QED — he’s Kell negative. What does it mean if I'm rhesus negative? I wish I could help more. Wouldn’t dominate genes … dominate? Wait another 3 … … He would have died had I taken that advice. I hope your two Kell positive sons’ future reproduction will be lucky and their partners are successfully treated by modern OBs if the babies get the K gene! For simplicity’s sake we’ll say brown eyes are “B” and blue eyes are “b”. Even if genetically otherwise they SHOULD express K or k, they don’t or barely do. Any university would probably have such an expert that you could email. Your Guide to Prenatal Tests and Doctor Visits. This is in addition to the ABO blood groups that most people know about. . I have to disagree with the midwife Kell antigen negative blood is not rare. Anti-K antibodies, for example, bind to the 'Kell antigen' on red blood cells. This means there is a 91% chance your husband is kell negative too! To have Kell positive blood means you have at least one of the Kell antigens on your red blood cells. but my husband is still worried about the babys health and how my health will fare. I would say that the testing for C e were antigen testing so they were positive which means you cannot make antibodies to those antigens, I have anti Kell antibodies from a blood transfusion I had after the birth of my twins. The drs will need to do invitro transfusions into the placentas ; however baby A’s is close to her front belly but baby B’s placenta is planted towards her back and that makes it very difficult to perform the transfusions. Did they test your husband for both K1 (Kell) and K2 (Cellano) genes, or was it just a blood test? I worry, a little, for my half-brother and my sister’s son, that they will have trouble if they want 2 kids, or if they have a partner who has had a prior Kell+ transfusion to react to. If the mother is Kell positive but the dad is not Kell positive, then the fetus will be unharmed by the mother’s body either way. For this reason, Kell typing of the father is the primary step in the management of Kell disease in pregnancy. We have patients getting tranfused liters of K+ blood who don’t ever develop antibodies, much less women from their babies. In reference to any weed related matter, often used as a code word. If your fetus is Kell+ your body will not attack it because it is the same as your blood type. And generally, that’s not a problem. Thankful to The Lord! I’m female with the normal blood type O+ if the mother has anti kell anti bodies and the father has a kell positive (heterozygous) Kk. But it is actually MUCH MUCH MORE COMMON to NOT develop antibodies. I’m still confused about the Kk vs. KK terminology. First, I am very sorry for your losses. The person who proposed to my has the blood type O+ but with kell antigens He is 100% the father as well. Does this mean my SS2 has a Kell positive blood type and can I get him tested to see? Stress can also hurt you and the baby. This blood type is present in about 33% in Caucasians, 24% in African American, 29% in Hispanic, and 27% in Asian. I believe, if I understand the timeline, this is your first baby since you contracted the anti-kell antibodies. I’m sure a proper medical doctor would be able to figure it out. For a few years I’ve been wondering how many other women.. I’m 15 weeks pregnant and my blood work says I am ‘A positive’, ‘negative’ Coombs indirect but ‘Ccee kell positive’. I had two miscarriages a year ago. So as I understand all my other babies were kell negative and if this baby is kell postive my body will give this baby a chance ? Either way, I wish you the best of luck!! Sorry, your blog cannot share posts by email. If you and the father and both kell neg then your child will be kell neg. Kell would have also showed up on your initial blood test. I feel like even if the baby is negative and so is my husband that there could still be problems with myself? I have had two healthy pregnancies – with my first being a girl and my second being a boy. Your little girl must be Kell+ and #9 must be Kell+ or your body would not be making antigens. Gladys Tan. Should my worries stop or is their any threats to my baby girl?.thank u so much. It took a toll on our relationship. I am little k cellano negative O positive is it hard for me to get blood if needed, please reply as I will need a operation soon I am little k negative o positive HOWEVER, just being from England (which the name Cary is) means your ancestors had a 9% chance of carrying the gene. Usually the blood is taken from the baby’s cord while it is attached to the placenta following delivery. They all have irregular antibodies. I am very, very glad baby #9 is doing well and I hope he or she has zero problems before, during, or after the birth. I sincerely hope this reply finds you well and delivered of a healthy second child!!!!! If the girl is either Kell positive or negative, it shouldn’t be a problem for her. The presence of Kell antibodies can be detected by maternal blood testing. There are still a lot of issues that medical science doesn’t have all the answers for and there are things they are finding out about blood antigens everyday. However, your should be safe on the Kell front. Advice… Other articles have told me that the antigen is very common, while the antibody is not so much. But in some breast cancers, the HER2 gene produces too many proteins. If the only plausible explanation is infidelity, then my goal would be to work on our marriage to stop the practice. At 33 weeks, she is with the range of viability so even if your body starts attacking they can induce your labor and ‘rescue’ her from a hostile uterine environment. Virtually everyone is Kell positive. (I have found that most doctors and blood centers don’t check for this because it is so rare.) First, let me congratulate you on your twins! If all four children are girls, and they each are Kk, then Kell positive blood is very likely to show up in the grandchildren. If you are more worried than you are in love, then end the relationship. Factors that determine transmission risk include whether a … My first daughter was born without incident. PLEASE let me know what the results were if you get a son tested for Kell!! Are they overrated or is it a big deal? I am in the same boat as this woman above. That means all the children except for the first, your daughter, and #9 will be almost axiomatically Kell negative. Please let me know how you are the baby are doing, and hopefully I will get the delightful news that you had the baby and both of you are healthy and happy. Does anyone stop to ask what “testing positive for coronavirus” means? I am anti-k (lowercase) so it is kind of like a cousin to Kell. How can this be? Thank you! In the ABO blood system, type O positive blood is common, about 36% of the population. Dear Melanie! (adsbygoogle = window.adsbygoogle || []).push({}); Post was not sent - check your email addresses! Hi have three boys after the first I had a blood tranfution went on two baby number two at 37 week they found out that i was kell postive but was not informed about it went on to baby three and found out at 17 wèek blood test that I was had kell postive partaner is negative what dose this mean for future pregnants and for the future of the three boys. Debbie from NY. This response is inaccurate. What happens if I don’t pass it on to the fetus and I’m positive but fetus is negative? In basic terms from what I read, Kell is where the mother's body attacks that fetus because it recognizes the fetus as a foreign invader. Please see Bombay phenotype for a similar situation, these people genetically maybe should be A, or B, but are missing the “foundation” so they don’t express the antigens. My ancestry is all European (mainly British) but my Kell result is K+k+ (and also Kp(a-b+)). Some people have it; some don’t. Her pregnancy with SS2 was just fine but she did have a C-sections and was "exposed" to this antigen or whatever it is. This is in addition to the ABO blood groups that most people know about. Now, we’ve all met families where all the kids were the same gender, so you know 50/50 doesn’t mean it will always split down the middle between two outcomes. Frankly, I am baffled as to how the antibodies got into your system without a blood transfusion or Kk hubby. I have some friends that I am trying to work with to petition some how to get blood Donors screened for kell. My third child, another daughter was born with no issues whatsoever. I am not sure why. The first pregnancy typically carries to term and produces a healthy infant, even if the infant is Kell positive and the mother is Kell negative. Quick question. My wife is pregnant with our fourth child and has had three prior C Sections. If two couples, let’s name them Ted (BB) & Alice (bb) and Bob (bb) & Jane (Bb), have children who marry each other then it is possible that all their grandchildren can have blue eyes in spite of the fact that two grandparents have the dominate brown-eyed gene. I can’t take the pressure anymore. However, not all of the ethnic groups share the same proportions of blood types. Antibodies can become unexpressive and the antibody screen will be negative and if your history is not known blood will not be antigen typed. I ended up demanding one. Of course, all of them could have brown eyes – it depends on the roll of the genetic dice when Mr. I would think that happened during your last pregnancy since you had no problem with your pregnancy. They were pregnant again but lost the baby at 23 weeks due to the problem. I love my wife and my kids, regardless of their origin. What happens if the mother is Kell positive and the father is Kell negative? People with Mcleod syndrome can have major issues, or actually be mostly OK (the person it was discovered in went to Harvard), but the gene for it is really close to the gene for chronic granulomatous disease which is bad business. Those antigens can doge a test more than people realize. Le signe + ou - correspond au rhésus. Since I have B negative blood, and my partner O positive I did the direct and indirect Coombs tests after both of my losses to check for RH issues, and they were negative. 5 yearsz ago i had my 1st son and had to have an emergency c-section which caused me to have blood transfusions to save my life. My wife has never had a transfusion nor needle stick. If you test positive, know what protective steps to take to prevent others from getting sick. Just make sure s/he remembers/knows your last pregnancy had this issue. A Kell positive man can cause serious problems for his reproductive partners after the first pregnancy, because a Kell negative mother’s body will develop a Kell alloimmunization — which means that her body would attack a Kell positive fetus as “foreign” and the result is fetal or neonatal death. I didn’t have them in my first and haven’t had a transfusion. I appreciate your help. Either the Kell did not ‘turn on’ and make itself known, or your mom’s body doesn’t have a profound alloimmunizational response. I had my first two babies via midwife, so I understand the desire for a low-intervention pregnancy and delivery, but if your wife has the anti-Kell antigens then the pregnancy is officially high risk and will need to go the full biomedical intervention route. Yes, Rh and Kell antibodies are a concern because tend to be relatively immunogenic and cause more severe hemolytic disease of the newborn because they are expressed by a fetus so early and women lose babies. Please understand, I have thought long and hard about this before posting… whatever the answer, the outcome will not end my marriage. So no, it is not rare. I am A- with Kell and Kidd antibodies. Like the punnett square shows, I have a 50% chance of passing it on to baby. As far as I know (and remember I’m not an MD so if your doctor says otherwise listen to him/her!) So how do you know he is Kell antigen positive. Also, there are HUNDREDS of antigens a partner could pass to baby that mother doesn’t have– many in the Rh system, Kell system, Kidd system, Duffy, Dombrock, etc. The baby is ok, but now I’m really worried about my next pregnancies. If your body had a really strong response vis-a-vis antigens, then only your body can handle your blood, plasma, ect … Also, a really strong anti-Kell response by your body might indicate a significant risk for your next fetus, in spite of all the medical technology, if it is Kell positive too. 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